ProxAI

Your interface picks the chassis.

Not catalog-first. Target-first.
Four binder chassis, chosen strictly on the merits of your binding interface.

Binder Repertoire
Antibody Fragments
Chassis 01

Antibody

Fab / scFv designs with established manufacturing and regulatory precedent.

Best For: Extracellular targets and therapeutic translation.
Use Cases:
IND-enabling biologic Therapeutic translation Diagnostics & Lab Reagents
Nanobodies
Chassis 02

Nanobody

Single-domain VHH framework with camelid-derived loop flexibility.

Best For: Concave epitopes, cryptic pockets, intrabody applications.
Use Cases:
Cryptic epitope PPI disruptor bioPROTAC mRNA-ENCODED
Minibinders
Chassis 03

Minibinders

De novo scaffolds offering high stability and precise interface targeting.

Best For: Compact and hydrophobic interfaces. Highly stable.
Use Cases:
PPI disruptor Intracellular bioPROTAC mRNA-ENCODED
Cyclic Peptides
Chassis 04

Cyclic Peptides

Constrained macrocycles with cell permeability and oral bioavailability potential.

Best For: Flat PPI interfaces and shallow groove binding. Cell penetration.
Use Cases:
Ortho & Allosteric ligand Payload vector (PDC)

Operational HQ

Montreal Clinical Research Institute (IRCM)
IRCM Building - ProxAI Headquarters IRCM Logo

> Wet Lab Infrastructure

Embedded within the prestigious IRCM, our physical laboratory bridges the critical gap between in silico generation and in vitro reality.

> High-Throughput Validation

Rapid, large-scale screening of computationally engineered binders. Executing proprietary validation workflows within native cellular contexts.

> Translational Excellence

Direct integration with top-tier microscopy, genomics, proteomics, immunology, and oncology resources, enabling accelerated development pipelines.